What is LADA?

LADA is a slow-progressing form of autoimmune diabetes that shares similarities with both Type 1 and Type 2 diabetes. It occurs when the immune system mistakenly attacks insulin-producing beta cells in the pancreas. However, unlike Type 1 diabetes, which typically develops in childhood or adolescence, LADA emerges in adulthood and progresses more gradually.

How is LADA Different from Type 2 Diabetes?

LADA is often initially mistaken for Type 2 diabetes because it develops in adulthood and may respond to lifestyle changes or oral medications at first. However, over time, insulin production continues to decline, and most individuals with LADA will require insulin therapy. Key differences include:

Age of Onset: LADA typically appears in adults over 30.
Progression: It progresses more slowly than Type 1 but faster than Type 2.
Autoimmune Markers: LADA is confirmed through the presence of autoantibodies, which are not found in Type 2 diabetes.
Insulin Dependence: While people with Type 2 diabetes may manage their condition with diet, exercise, and oral medications, LADA eventually requires insulin therapy.

Signs & Symptoms of LADA

Unexplained weight loss
Persistent high blood sugar levels despite oral medications
Increased thirst and frequent urination
Fatigue and weakness
Blurred vision

Diagnosis & Testing

If Type 2 diabetes treatments are ineffective or if there are signs of autoimmune involvement, healthcare providers may recommend tests such as:
GAD Antibodies Test: To detect autoantibodies targeting insulin-producing cells
C-Peptide Test: To assess how much insulin the pancreas is producing

Managing LADA

Since LADA is an autoimmune condition, it requires a different management approach than Type 2 diabetes:

Early Insulin Therapy: To preserve remaining beta cell function and prevent complications
Low-Carb, Nutrient-Dense Diet: Helps maintain stable blood sugar levels
Regular Monitoring: Keeping track of blood glucose levels to adjust treatment as needed
Exercise & Lifestyle Modifications: Helps improve insulin sensitivity and overall health

• Why Does It Matter?

Misdiagnosing LADA as Type 2 diabetes can lead to ineffective treatment and unnecessary complications. Raising awareness about this condition ensures proper diagnosis and management, ultimately improving long-term health outcomes.

If you or someone you know has been struggling with managing diabetes despite following treatment plans, it may be worth discussing LADA with a healthcare professional.